Effects of nicotine on Drosophila development: genes, neurotransmitters and toxicology

Effects of nicotine on Drosophila development: genes, neurotransmitters and toxicology

Project Abstract

Nicotine is the chemical in tobacco associated to addiction, yet little is known about the changes nicotine causes that produce addiction. My lab uses Drosophila, the common fruit fly, to discover the mechanisms for nicotine’s effects. Students working in this project will expose flies to nicotine, dissect brains, stain them, and use fluorescence and confocal microscopy to characterize nicotine’s effects on neurotransmitters and on proteins associated to nicotine metabolism. Students will also use molecular biology to identify genes involved in nicotine’s effects.

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